这些 zhè xiē 药 yào 的 de 效果 xiàoguǒ 起初 qǐchū 非常 fēicháng 好 hǎo ,但 dàn 后来 hòulái 逐渐 zhújiàn 失效 shī xiào .

The drugs work well at first but gradually lose their effectiveness.

起初 qǐchū 天气 tiānqì 很 hěn 好 hǎo ,后来 hòulái 才 cái 开始 kāishǐ 下 xià 雨 yǔ .

It was fine to begin with and then It'started to rain.

后来 hòulái 他 tā 东漂西荡 dàng 又 yòu 回到 huí dào 了 le 苏必利尔 ěr 湖 hú .

Then he drifted back to Lake Superior.

就 jiù 是 shì 在 zài 绘画 huì huà 课上他 tā 遇到 yùdào 了 le 安东尼 Ān dōng ní -普鲁斯特 Pǔ lǔ sī tè , 他们 tā men 后来 hòulái 成为 chéngwéi 终身 zhōngshēn 朋友 péngyou .

It was there that he met Antonin Proust , who was to become a great lifetime friend.